Immunohistochemical changes in rat testis related to the local beta-hCG injection.

In recent years, studies made concerning the treatment of obesity, it has been observed that weight loss is accelerated by human chorionic gonadotropin (hCG) hormone preparation used for hypothalamic dysfunction in obesity treatment single dose of subcutaneously to abdominal region. Our aim was to observe immunohistochemical changes in male rats, were fed ad libitum with cafeteria diet to gain weight, related to the local hCG injection in testis. In our study, 10 male obese and 10 non-obese male rats were used. In each group, single dose of subcutaneous beta-hCG injection has been applied to 7 rats for 5 weeks in 5 days of the week, and placebo has been applied to the remaining 3 rats. Following the injection, the tissues were evaluated immunohistochemically. As a result of our studies, there weren't any clear differences in testis and it was thought that the increases and decreases in the number of hormone receptors may be seen in parallel with the increases and decreases in hormone levels. As a conclusion, we believe that the implementation of beta-hCG in addition to diet has no effect on testis. [ABSTRACT FROM AUTHOR]