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Oxovanadium(IV) Schiff Base Complex Derived From Phenylalanine Analogue Containing 2,3-Diaminopropionic Acid (DAP): Synthesis, Computational Study, and Biological Evaluation.
- Source :
-
Synthesis & Reactivity in Inorganic, Metal-Organic, & Nano-Metal Chemistry . 2015, Vol. 45 Issue 3, p455-467. 13p. - Publication Year :
- 2015
-
Abstract
- Reduced Schiff base ligand by condensation of phenylalanine analogue containing 2,3-diaminopropionic acid (DAP) with salicylaldehyde and its oxovanadium(IV) complex have been prepared. Chemical and structural properties were fully characterized. Density functional theory was used to pin down the structure combined with IR. The natural bond orbital analysis and energy calculations indicate that tetracoordinated complex of R-type is the most probable structure where vanadium atom is coordinated to 2 × Ophenolateand 2 × Nimineof the ligand. By biological evaluation, the metal complex exhibits antibacterial activity against four bacterial strains and antitumor activity against two tumor cell lines. [ABSTRACT FROM PUBLISHER]
Details
- Language :
- English
- ISSN :
- 15533174
- Volume :
- 45
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Synthesis & Reactivity in Inorganic, Metal-Organic, & Nano-Metal Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 98903048
- Full Text :
- https://doi.org/10.1080/15533174.2013.841205