Unresectable Perineal Cuniculatum Carcinoma: Partial Remission Using Systemic Isotretinoin and Interferon-α2a Therapy.

A case study describing perineal carcinoma cuniculatum (CC) complicating giant condyloma in an HIV-infected patient is presented. The patient was treated with combined systemic isotretinoin and interferon therapy when surgery, radiotherapy or chemotherapy could not be used. Topics covered include the medical history of the patient, the clinical presentation of CC, and the management and outcome of the patient.