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Variant Analysis of CARD14 in a Chinese Han Population with Psoriasis Vulgaris and Generalized Pustular Psoriasis.
- Source :
-
Journal of Investigative Dermatology . Dec2014, Vol. 134 Issue 12, p2994-2996. 3p. - Publication Year :
- 2014
-
Abstract
- The article presents a study which examines the analysis of caspase recruitment domain family member 14 (CARD14) variants in the Chinese Han patients with psoriasis vulgaris (PsV) and generalized pustular psoriasis (GPP). Findings reveal five rare variants including p.Met119Val, p.Arg166His, and p.Ala216Thr. It suggests the significant role of the rare CARD14 variants in the pathogenesis of GPP.
Details
- Language :
- English
- ISSN :
- 0022202X
- Volume :
- 134
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Journal of Investigative Dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 99335249
- Full Text :
- https://doi.org/10.1038/jid.2014.269