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Parkin western blotting is useful for identification of patients with Parkin-related Parkinson's disease.

Authors :
Koentjoro, Brianada
Park, Jin-Sung
Sue, Carolyn M.
Source :
Journal of Neurology, Neurosurgery & Psychiatry. Dec2014, Vol. 85 Issue 12, p1436-1437. 2p. 1 Graph.
Publication Year :
2014

Abstract

The article offers information on diagnosis of patients with Parkinson's disease (PD) with use of western blotting technique to identify PD related genes. It states that western blotting was performed on fibroblast cells derived from PD patients having known genetic mutations. It concludes that western blotting is efficient in diagnosis of PD as it identifies PD protein expression but further mutational analysis should also be done to eradicate false positive results due to missense mutation.

Details

Language :
English
ISSN :
00223050
Volume :
85
Issue :
12
Database :
Academic Search Index
Journal :
Journal of Neurology, Neurosurgery & Psychiatry
Publication Type :
Academic Journal
Accession number :
99653410
Full Text :
https://doi.org/10.1136/jnnp-2014-308142