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Synthesis and anti-cancer cell activity of pseudo-ginsenoside Rh2.
- Source :
-
Steroids . Dec2014, Vol. 92, p1-6. 6p. - Publication Year :
- 2014
-
Abstract
- β- d -Glucopyranoside,(3β,12β,20E)-12,25-dihydroxydammar-20(22)-en-3-yl (pseudo-ginsenoside Rh2) and its 20Z-isomer were synthesized from ginsenoside Rh2 under a mild condition, via a simple three-step called acetylation, elimination–addition and saponification. In addition, their activities were evaluated by eight different human tumor cells, compared with ginsenoside Rh2 group. Results indicated that the reaction in the side chain might greatly enhance the anti-proliferative activity of ginsenosides. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0039128X
- Volume :
- 92
- Database :
- Academic Search Index
- Journal :
- Steroids
- Publication Type :
- Academic Journal
- Accession number :
- 99735057
- Full Text :
- https://doi.org/10.1016/j.steroids.2014.08.021