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EFECTO DE LA MACA ROJA(Lepidiummeyenii) SOBRE LOS NIVELES DE IFN-γ EN RATAS OVARIECTOMIZADAS.

Authors :
Leiva-Revilla, Johanna
Guerra-Castañon, Félix
Olcese-Mori, Paola
Lozada, Iván
Rubio, Julio
Gonzales, Carla
Gonzales, Gustavo F.
Source :
Revista Peruana de Medicina Experimental y Salud Pública. 2014, Vol. 31 Issue 4, p683-688. 6p. 1 Chart, 1 Graph.
Publication Year :
2014

Abstract

Objectives. Compare the effect of different doses of red maca on gamma interferon (IFN-γ) levels in ovariectomized rats (OVX). Materials and methods. Adult female rats were randomly divided into the following six groups: Group 1: pseudo-ovariectomized rats (PO); Group 2: OVX rats; Group 3: OVX rats treated with 4 ug/kg estradiol; and Group 4, 5 and 6: OVX rats treated with red maca extracts with 2.15, 4.3 and 8.6 mg polyphenols/body weight kilogram, respectively. Results. OVX rats showed low levels of IFN-γ compared to PO rats. Estradiol and red maca reversed the effect of ova-riectomy on the IFN-γ levels. A positive dose-response effect of red maca on IFN-γ levels was shown (r = 0.57, p <0.05). Conclusions. Red maca administration increases levels of IFN-γ in ovariectomized rats. [ABSTRACT FROM AUTHOR]

Details

Language :
Spanish
ISSN :
17264634
Volume :
31
Issue :
4
Database :
Academic Search Index
Journal :
Revista Peruana de Medicina Experimental y Salud Pública
Publication Type :
Academic Journal
Accession number :
99817953
Full Text :
https://doi.org/10.17843/rpmesp.2014.314.118