Back to Search Start Over

Bromotriphenylphosphonium Salt Promoted One-Pot Cyclization to 2-Fluoroalkyl-Substituted Indoles.

Authors :
Zeng-xue Wang
Tai-feng Zhang
Qing-wen Ma
Wei-gui Ni
Source :
Synthesis. 2014, Vol. 46 Issue 24, p3309-3314. 6p.
Publication Year :
2014

Abstract

2-Fluoroalkyl-substituted indoles were prepared in moderate to excellent yields through bromotriphenylphosphonium salt promoted ring formation with fluorine-containing carboxylic acids in the presence of triethylamine in toluene at reflux temperature. A range of 2-fluoroalkyl-substituted indole derivatives can be conveniently prepared. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397881
Volume :
46
Issue :
24
Database :
Academic Search Index
Journal :
Synthesis
Publication Type :
Academic Journal
Accession number :
99835379
Full Text :
https://doi.org/10.1055/s-0034-1379030