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Chimera: a Bioconductor package for secondary analysis of fusion products.
- Source :
-
Bioinformatics . Dec2014, Vol. 30 Issue 24, p3556-3557. 2p. - Publication Year :
- 2014
-
Abstract
- Summary: Chimera is a Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools; current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools. Fusions are then easily manipulated with standard R functions or through the set of functionalities specifically developed in Chimera with the aim of supporting the user in managing fusions and discriminating false-positive results.Availability and implementation: Chimera is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org.Contact: raffaele.calogero@unito.itSupplementary information: Supplementary data are available at Bioinformatics online. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13674803
- Volume :
- 30
- Issue :
- 24
- Database :
- Academic Search Index
- Journal :
- Bioinformatics
- Publication Type :
- Academic Journal
- Accession number :
- 99841722
- Full Text :
- https://doi.org/10.1093/bioinformatics/btu662