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Vγ9Vδ2-T cells as antigen presenting cells for iNKT cell based cancer immunotherapy.

Authors :
Werter, Inge M.
Schneiders, Famke L.
Scotet, Emmanuel
Verheul, Henk M.W.
de Gruijl, Tanja D.
van der Vliet, Hans J.
Source :
OncoImmunology. Sep2014, Vol. 3 Issue 9, pN.PAG-N.PAG. 1p.
Publication Year :
2014

Abstract

CD1d-restricted invariant natural killer T cells (iNKT) constitute an important immunoregulatory T-cell subset involved in the induction of antitumor immune responses. Here, we provide a view on the recent observation that Vγ9Vδ2-T cells, through trogocytosis of CD1d-containing membrane fragments, have the capacity to act as antigen presenting cells for iNKT. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
21624011
Volume :
3
Issue :
9
Database :
Academic Search Index
Journal :
OncoImmunology
Publication Type :
Academic Journal
Accession number :
99964403
Full Text :
https://doi.org/10.4161/21624011.2014.955343