Meningococcal carriage: the dilemma of 4CMenB vaccine.

The author discusses meningococcal carriage as the dilemma of the multicomponent protein-based vaccine (4CMenB) Bexsero. He says that despite the small carriage reduction, the reproduction number for meningococci should be considered. He also discussed the average number of secondary infections produced by an infected individual and the use of comprehensive disease surveillance to track the efficacy of 4CMenB vaccine.