The presentation of serum lipids and uric acid in cerebral ischemia.

In this study, we examine the relationship between serum lipids and uric acid in nonembolic cerebral ischemia (NECI) patients. The serum level of total cholesterol (TC) and uric acid increased significantly in male, while TC and triglyceride in female patients. The increase of TC was more significance in female patients. There was no correlation between serum lipids and uric acid in NECI patients or controls, but a significant correlation between triglyceride and uric acid was present in diabetic patient. These findings suggest that lipids and uric acid are essential risk factors for cerebral ischemia in our population. Although there is no association of their metabolism, their parallellic abnormality in diabetic NECI individuals indicates that some possible factors changing in diabetics can influence the metabolic pathway of both lipid and uric acid, which may promote each other for atherogenesis in diabetics.