[Renal clear-cell adenocarcinoma and type B lymphomatous proliferation: a fortuitous association?].

Purpose: To discuss the potentially fortuitous occurrence of both renal carcinoma and B-cell malignant proliferation and its physiopathology.
Methods: We describe a series of eight patients presenting with both diseases.
Results: In these patients renal carcinoma was associated with either malignant non-Hodgkin lymphoma (seven cases) or multiple myeloma (one case). Of the eight patients three had both malignancies within the same renal tumor.
Conclusion: Though this association is unusual, it may not be fortuitous. Its physiopathology is discussed in regard to either growth factor synthesis within the renal tumor or mutations in tumor-suppressor genes.