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[Vitamin D deficiency. Easy to diagnose, often overlooked].

Authors :
Glerup H
Eriksen EF
Source :
Ugeskrift for laeger [Ugeskr Laeger] 1999 Apr 26; Vol. 161 (17), pp. 2515-21.
Publication Year :
1999

Abstract

On the basis of five cases the typical clinical picture of patients with severe vitamin D deficiency is presented. The diagnosis can easily be mistaken and it is not uncommon that rheumatic or malignant diseases are suspected instead. By using a simple screening blood test consisting of 25-OH-vitamin D, PTH and alkaline phosphatase most cases will be diagnosed correctly. Important risk factors are reviewed, the most important being: elderly > 70 years, persons with low exposure to direct sunlight, gastrointestinal diseases and persons in anti-convulsive treatment. A treatment regimen consisting of oral supplementation of 1000-1500 mg calcium + 1000 IU vitamin D to patients with an isolated low 25-OH-vitamin D (< 20 nmol/l) is recommended. If the patient also has raised values of PTH or alkaline phosphatase an intramuscular dose of 100,000 IU ergocalciferol pr week for one month is given.

Details

Language :
Danish
ISSN :
0041-5782
Volume :
161
Issue :
17
Database :
MEDLINE
Journal :
Ugeskrift for laeger
Publication Type :
Academic Journal
Accession number :
10327872