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Acarbose-induced generalised erythema multiforme.

Authors :
Kono T
Hayami M
Kobayashi H
Ishii M
Taniguchi S
Source :
Lancet (London, England) [Lancet] 1999 Jul 31; Vol. 354 (9176), pp. 396-7.
Publication Year :
1999

Abstract

A 58-year-old man with diabetes mellitus was treated with acarbose 300 mg daily. 13 days after the start of treatment with acarbose, generalised erythema multiforme developed with blood eosinophilia. Tissue eosinophilia was also found histologically. A challenge test for acarbose confirmed allergic reaction clinically and histologically.

Subjects

Subjects :
Acarbose
Biopsy
Diabetes Mellitus, Type 2 pathology
Drug Eruptions pathology
Eosinophilia chemically induced
Eosinophilia pathology
Erythema Multiforme pathology
Humans
Hypoglycemic Agents therapeutic use
Male
Middle Aged
Skin drug effects
Skin pathology
Trisaccharides therapeutic use
Diabetes Mellitus, Type 2 drug therapy
Drug Eruptions diagnosis
Erythema Multiforme chemically induced
Hypoglycemic Agents adverse effects
Trisaccharides adverse effects

Details

Language :
English
ISSN :
0140-6736
Volume :
354
Issue :
9176
Database :
MEDLINE
Journal :
Lancet (London, England)
Publication Type :
Report
Accession number :
10437876
Full Text :
https://doi.org/10.1016/S0140-6736(99)02135-2
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