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[Lipid inhibitors of phospholipase A2].

Authors :
Bragina NA
Chupin VV
Bulgakov VG
Shal'nev AN
Source :
Bioorganicheskaia khimiia [Bioorg Khim] 1999 Feb; Vol. 25 (2), pp. 83-96.
Publication Year :
1999

Abstract

Results of studies of lipid inhibitors of phospholipase A2 are reviewed with a special emphasis on substrate specificity, special features of interfacial catalysis, and methods for the determination of the enzyme activity. The biological function of intracellular phospholipases is considered, and the possible use of inhibitors of a lipid nature for the modulation of the enzyme activity in pathological states of the human organism is discussed.

Details

Language :
Russian
ISSN :
0132-3423
Volume :
25
Issue :
2
Database :
MEDLINE
Journal :
Bioorganicheskaia khimiia
Publication Type :
Academic Journal
Accession number :
10495898