Screening for acyclovir-resistant herpes simplex virus isolates from clinical samples.

Authors :: Mah IW
Kuo BI
Wei HY
Tsai CH
Liu WT
Source :: Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology [Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi] 1997 Feb; Vol. 30 (1), pp. 51-4.
Publication Year :: 1997
Abstract: The ID90 or ID50 values of acyclovir for the herpes simplex virus strains isolated in VGH-Taipei were determined by plaque reduction method. Twenty HSV isolates of 1980's (1980-1985) and thirty of 1990's (1990-1995) were subjected to plaque reduction assay for susceptibility test to acyclovir. There were fifteen HSV isolates of 1990's whose ID90 were higher than those of 1980's, indicating a trend of more acyclovir resistant isolates in 1990's.

Subjects :: Animals
Chlorocebus aethiops
Drug Resistance, Microbial
Humans
Vero Cells
Acyclovir pharmacology
Antiviral Agents pharmacology
Simplexvirus drug effects

Language :: English
ISSN :: 0253-2662
Volume :: 30
Issue :: 1
Database :: MEDLINE
Journal :: Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology
Publication Type :: Academic Journal
Accession number :: 10592810

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