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Application of comparative molecular field analysis to dopamine D2 partial agonists.
- Source :
-
Bioorganic & medicinal chemistry [Bioorg Med Chem] 1999 Nov; Vol. 7 (11), pp. 2453-6. - Publication Year :
- 1999
-
Abstract
- Comparative molecular field analysis (CoMFA) has been applied to novel D2 partial agonists. Due to the predictability of the CoMFA model across different series of D2 partial agonists, we believe these compounds are binding to the D2 agonist receptor in the conformation and alignment described herein.
- Subjects :
- Models, Molecular
Structure-Activity Relationship
Receptors, Dopamine D2 agonists
Subjects
Details
- Language :
- English
- ISSN :
- 0968-0896
- Volume :
- 7
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 10632054
- Full Text :
- https://doi.org/10.1016/s0968-0896(99)00201-1