Back to Search Start Over

Hepatosplenic B-cell lymphoma associated with hemophagocytic syndrome: a case report.

Authors :
Kwon SY
Lee JJ
Chung IJ
Kim HJ
Park MR
Kim HS
Park CS
Source :
Journal of Korean medical science [J Korean Med Sci] 1999 Dec; Vol. 14 (6), pp. 671-4.
Publication Year :
1999

Abstract

While T-cell non-Hodgkin's lymphoma (NHL) associated with hemophagocytic syndrome (HPS) has been frequently observed, B-cell NHL associated with HPS has been rarely reported. We report a case of hepatosplenic B-cell lymphoma associated with HPS in a 41-year-old woman who presented with fever of unknown origin. An abdominal CT scan revealed splenomegaly with focal splenic infarction. Splenectomy and a liver wedge biopsy showed sinusoidal-pattern infiltration of medium to large tumor cells with positive reaction to a B-lymphocyte marker. Findings on bone marrow examination showed proliferation of histiocytes with avid hemophagocytosis.

Details

Language :
English
ISSN :
1011-8934
Volume :
14
Issue :
6
Database :
MEDLINE
Journal :
Journal of Korean medical science
Publication Type :
Academic Journal
Accession number :
10642947
Full Text :
https://doi.org/10.3346/jkms.1999.14.6.671