Synthesis and antimycobacterial activity of some N1-[1-[3-aryl-1-(pyridin-2-, 3-, or 4-yl)-3-oxo]propyl]-2- pyridinecarboxamidrazones.

Authors :: Mamolo MG
Falagiani V
Vio L
Banfi E
Source :: Farmaco (Societa chimica italiana : 1989) [Farmaco] 1999 Nov-Dec; Vol. 54 (11-12), pp. 761-7.
Publication Year :: 1999
Abstract: N1-[1-[3-aryl-1-(pyridin-2,3-, and 4-yl)-3-oxo[propyl]-2- pyridinecarboxamidrazone derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed interesting activity against a strain of Mycobacterium tuberculosis and a strain of Mycobacterium avium.

Subjects :: Microbial Sensitivity Tests
Pyridines chemistry
Spectrum Analysis
Anti-Bacterial Agents pharmacology
Mycobacterium avium drug effects
Mycobacterium tuberculosis drug effects
Pyridines chemical synthesis
Pyridines pharmacology

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