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The induction of c-Fos in the NTS after taste aversion learning is not correlated with measures of conditioned fear.
- Source :
-
Behavioral neuroscience [Behav Neurosci] 2000 Feb; Vol. 114 (1), pp. 99-106. - Publication Year :
- 2000
-
Abstract
- The induction of c-Fos-like immunoreactivity (c-FLI) in the nucleus of the solitary tract (NTS) has been shown to be correlated with behavioral expression of a conditioned taste aversion (CTA). However, because this cellular response is also dependent on an intact amygdala, it may represent the activation of a stress-related autonomic response. The present experiments addressed this possibility by evaluating the correlation between c-FLI in the intermediate division of the NTS (iNTS) and 2 measures of conditioned fear: freezing and changes in mean arterial pressure (MAP) and heart rate (HR). Exposure to the taste conditioned stimulus (CS) resulted in a marked induction of c-FLI in the iNTS, whereas exposure to a fear CS did not. Further, exposure to a taste CS did not selectively lead to increases in MAP or HR. Results suggest that induction of c-FLI in the iNTS may reflect the activation of a cell population whose function is unique to the CTA paradigm.
- Subjects :
- Animals
Blood Pressure physiology
Brain Mapping
Heart Rate physiology
Male
Motor Activity physiology
Neurons physiology
Rats
Rats, Long-Evans
Avoidance Learning physiology
Conditioning, Classical physiology
Fear physiology
Proto-Oncogene Proteins c-fos metabolism
Solitary Nucleus physiology
Taste physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0735-7044
- Volume :
- 114
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Behavioral neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 10718265