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[Recently discovered herpes viruses explain the etiology of well-known diseases].
- Source :
-
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 1999 Dec 10; Vol. 119 (30), pp. 4463-6. - Publication Year :
- 1999
-
Abstract
- Three new members of the family of human herpesviruses (HHVs) have been identified in less than a decade, HHV 6 7 and 8. HHV-6 and HHV-7, both infecting T-lymphocytes and phylogenetically related to cytomegalovirus, were identified as causative agents of exanthema subitum. In addition, HHV-6 has been reported to manifest central nervous system tropism and to be frequently detected in normal brain tissue, but has also been associated with febrile seizures. HHV-7 has been suggested to be involved in the development of pityriasis rosea, but has also been found to occur in normal dermal tissue. HHV-8, related to Epstein-Barr virus and infecting B-lymphocytes, was the first herpesvirus to be identified with molecular techniques. Recent research has been focused on the involvement of proteins expressed by HHV-8 in the pathogenesis of two rare tumours, Kaposi's sarcoma and body-cavity B-cell lymphomas.
- Subjects :
- Exanthema Subitum pathology
Exanthema Subitum virology
Fever virology
Herpesviridae Infections diagnosis
Herpesviridae Infections pathology
Humans
Lymphoma, B-Cell pathology
Lymphoma, B-Cell virology
Multiple Sclerosis virology
Pityriasis Rosea pathology
Pityriasis Rosea virology
Sarcoma, Kaposi pathology
Sarcoma, Kaposi virology
Seizures, Febrile virology
Herpesviridae Infections etiology
Herpesvirus 6, Human isolation & purification
Herpesvirus 7, Human isolation & purification
Herpesvirus 8, Human isolation & purification
Subjects
Details
- Language :
- Swedish
- ISSN :
- 0029-2001
- Volume :
- 119
- Issue :
- 30
- Database :
- MEDLINE
- Journal :
- Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
- Publication Type :
- Academic Journal
- Accession number :
- 10827485