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[Recently discovered herpes viruses explain the etiology of well-known diseases].

Authors :
Bergström T
Source :
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke [Tidsskr Nor Laegeforen] 1999 Dec 10; Vol. 119 (30), pp. 4463-6.
Publication Year :
1999

Abstract

Three new members of the family of human herpesviruses (HHVs) have been identified in less than a decade, HHV 6 7 and 8. HHV-6 and HHV-7, both infecting T-lymphocytes and phylogenetically related to cytomegalovirus, were identified as causative agents of exanthema subitum. In addition, HHV-6 has been reported to manifest central nervous system tropism and to be frequently detected in normal brain tissue, but has also been associated with febrile seizures. HHV-7 has been suggested to be involved in the development of pityriasis rosea, but has also been found to occur in normal dermal tissue. HHV-8, related to Epstein-Barr virus and infecting B-lymphocytes, was the first herpesvirus to be identified with molecular techniques. Recent research has been focused on the involvement of proteins expressed by HHV-8 in the pathogenesis of two rare tumours, Kaposi's sarcoma and body-cavity B-cell lymphomas.

Details

Language :
Swedish
ISSN :
0029-2001
Volume :
119
Issue :
30
Database :
MEDLINE
Journal :
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke
Publication Type :
Academic Journal
Accession number :
10827485