Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator.

Authors :: Magdolen V
Arroyo de Prada N
Sperl S
Muehlenweg B
Luther T
Wilhelm OG
Magdolen U
Graeff H
Reuning U
Schmitt M
Source :: Advances in experimental medicine and biology [Adv Exp Med Biol] 2000; Vol. 477, pp. 331-41.
Publication Year :: 2000

Subjects :: Amidines chemical synthesis
Amidines pharmacology
Amiloride chemistry
Amiloride pharmacology
Animals
Benzamidines chemistry
Benzamidines pharmacology
Guanidines chemistry
Guanidines pharmacology
Mice
Mice, Knockout
Models, Biological
Molecular Structure
Neoplasm Invasiveness
Neoplasm Proteins metabolism
Phenotype
Plasminogen Activator Inhibitor 1 deficiency
Plasminogen Activator Inhibitor 1 genetics
Plasminogen Activator Inhibitor 1 pharmacology
Plasminogen Activator Inhibitor 1 physiology
Plasminogen Activator Inhibitor 2 deficiency
Plasminogen Activator Inhibitor 2 genetics
Plasminogen Activator Inhibitor 2 pharmacology
Plasminogen Activator Inhibitor 2 physiology
Receptors, Cell Surface drug effects
Receptors, Cell Surface metabolism
Receptors, Urokinase Plasminogen Activator
Serine Proteinase Inhibitors chemical synthesis
Structure-Activity Relationship
Thiophenes chemical synthesis
Thiophenes pharmacology
Neoplasm Proteins antagonists & inhibitors
Serine Proteinase Inhibitors pharmacology
Serpins physiology
Urokinase-Type Plasminogen Activator antagonists & inhibitors

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