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[Trends in erythrocyte immunohematology reagents].
- Source :
-
Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine [Transfus Clin Biol] 2000 Jun; Vol. 7 Suppl 1, pp. 40s-43s. - Publication Year :
- 2000
-
Abstract
- Until the 1980s blood group reagents had been produced from human or animal plasmas. Since then, the main change has been the increase of the use of monoclonal antibodies in laboratory reagents. Today, they are the basis of most reagents for blood group typing. They include murine (hybridomas) and human (Epstein-Barr virus immortalized lymphocytes and phage display) antibodies. The use of these antibodies leads to standardized methods of production and a better definition of the specificity through international works. The main drawback is the lack of antibodies for some blood group antigens. However, in the future these methods will be confronted with the development of DNA-based methods.
- Subjects :
- Animals
Antibodies, Monoclonal immunology
Antibody Specificity
Blood Group Antigens immunology
Blood Grouping and Crossmatching methods
Blood Grouping and Crossmatching standards
Cell Line, Transformed
Epitopes immunology
Humans
Hybridomas immunology
Indicators and Reagents
Mice
Peptide Library
Blood Group Antigens analysis
Blood Grouping and Crossmatching trends
Subjects
Details
- Language :
- French
- ISSN :
- 1246-7820
- Volume :
- 7 Suppl 1
- Database :
- MEDLINE
- Journal :
- Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine
- Publication Type :
- Academic Journal
- Accession number :
- 10919223
- Full Text :
- https://doi.org/10.1016/s1246-7820(00)80015-4