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Drug-induced stabilization of covalent DNA topoisomerase I-DNA intermediates. DNA cleavage assays.
- Source :
-
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2001; Vol. 95, pp. 291-301. - Publication Year :
- 2001
- Subjects :
- Camptothecin analogs & derivatives
Cells, Cultured
DNA, Bacterial genetics
DNA, Bacterial metabolism
Electrophoresis, Polyacrylamide Gel
Enzyme Stability drug effects
Humans
Plasmids genetics
Sequence Analysis, DNA
Topoisomerase I Inhibitors
Antineoplastic Agents pharmacology
Camptothecin pharmacology
DNA Topoisomerases, Type I metabolism
DNA-Binding Proteins metabolism
Plasmids metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1064-3745
- Volume :
- 95
- Database :
- MEDLINE
- Journal :
- Methods in molecular biology (Clifton, N.J.)
- Publication Type :
- Academic Journal
- Accession number :
- 11089241
- Full Text :
- https://doi.org/10.1385/1-59259-057-8:291