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Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein.
- Source :
-
Journal of medicinal chemistry [J Med Chem] 2000 Nov 30; Vol. 43 (24), pp. 4575-8. - Publication Year :
- 2000
- Subjects :
- Carrier Proteins antagonists & inhibitors
Carrier Proteins blood
Cholesterol Ester Transfer Proteins
Crystallography, X-Ray
Humans
In Vitro Techniques
Propanolamines blood
Propanolamines chemistry
Stereoisomerism
Carrier Proteins chemistry
Cholesterol Esters blood
Glycoproteins
Propanolamines chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 0022-2623
- Volume :
- 43
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Journal of medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 11101348
- Full Text :
- https://doi.org/10.1021/jm000337b