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Intrathecal baclofen for dystonia: benefits and complications during six years of experience.

Authors :
Walker RH
Danisi FO
Swope DM
Goodman RR
Germano IM
Brin MF
Source :
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2000 Nov; Vol. 15 (6), pp. 1242-7.
Publication Year :
2000

Abstract

Fourteen patients with primary or secondary dystonia received intrathecal baclofen (ITB) through an implanted pump following a trial dose. Patients were selected for ITB trial if they had clinically unsatisfactory responses to oral antidystonic medications, including oral baclofen. Patients were rated using the Burke-Fahn-Marsden rating scale by a blinded rater after the dose of ITB was optimized. Five patients experienced improvement in symptoms as determined by a change in rating scale scores, although only two had a clear clinical benefit. Etiology of dystonia did not determine the efficacy of ITB therapy, as benefit or failure was seen in both primary and secondary dystonia.

Details

Language :
English
ISSN :
0885-3185
Volume :
15
Issue :
6
Database :
MEDLINE
Journal :
Movement disorders : official journal of the Movement Disorder Society
Publication Type :
Academic Journal
Accession number :
11104213
Full Text :
https://doi.org/10.1002/1531-8257(200011)15:6<1242::aid-mds1028>3.0.co;2-z