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Intrathecal baclofen for dystonia: benefits and complications during six years of experience.
- Source :
-
Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2000 Nov; Vol. 15 (6), pp. 1242-7. - Publication Year :
- 2000
-
Abstract
- Fourteen patients with primary or secondary dystonia received intrathecal baclofen (ITB) through an implanted pump following a trial dose. Patients were selected for ITB trial if they had clinically unsatisfactory responses to oral antidystonic medications, including oral baclofen. Patients were rated using the Burke-Fahn-Marsden rating scale by a blinded rater after the dose of ITB was optimized. Five patients experienced improvement in symptoms as determined by a change in rating scale scores, although only two had a clear clinical benefit. Etiology of dystonia did not determine the efficacy of ITB therapy, as benefit or failure was seen in both primary and secondary dystonia.
Details
- Language :
- English
- ISSN :
- 0885-3185
- Volume :
- 15
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Movement disorders : official journal of the Movement Disorder Society
- Publication Type :
- Academic Journal
- Accession number :
- 11104213
- Full Text :
- https://doi.org/10.1002/1531-8257(200011)15:6<1242::aid-mds1028>3.0.co;2-z