Back to Search
Start Over
Synthesis and antiproliferative activity of benzocyclobutacarbazol derivatives. A new class of potential antitumor agents.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2000 Dec 04; Vol. 10 (23), pp. 2589-91. - Publication Year :
- 2000
-
Abstract
- Several benzocyclobutacarbazol derivatives were synthesized and evaluated for their potential cytotoxic properties. A number of these compounds exhibited significant antiproliferative activity with concomitant interaction with the cell cycle and represent a new class of potential anticancer agents.
- Subjects :
- Animals
Carbazoles chemistry
Cyclobutanes chemistry
Drug Screening Assays, Antitumor
Mice
Tumor Cells, Cultured
Antineoplastic Agents chemical synthesis
Antineoplastic Agents pharmacology
Carbazoles chemical synthesis
Carbazoles pharmacology
Cyclobutanes chemical synthesis
Cyclobutanes pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 0960-894X
- Volume :
- 10
- Issue :
- 23
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 11128630
- Full Text :
- https://doi.org/10.1016/s0960-894x(00)00532-1