Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer.

Authors :: Yamamoto Y
Gaynor RB
Source :: The Journal of clinical investigation [J Clin Invest] 2001 Jan; Vol. 107 (2), pp. 135-42.
Publication Year :: 2001

Subjects :: Alzheimer Disease etiology
Anti-Inflammatory Agents, Non-Steroidal therapeutic use
Apoptosis genetics
Arthritis, Rheumatoid etiology
Asthma etiology
Cell Division genetics
Chemokines biosynthesis
Chemokines genetics
Cyclooxygenase 2
Cytokines biosynthesis
Cytokines genetics
Glucocorticoids therapeutic use
I-kappa B Kinase
I-kappa B Proteins metabolism
Immunosuppressive Agents therapeutic use
Inflammatory Bowel Diseases etiology
Isoenzymes biosynthesis
Isoenzymes genetics
NF-kappa B antagonists & inhibitors
NF-kappa B immunology
Nitric Oxide Synthase biosynthesis
Nitric Oxide Synthase genetics
Nitric Oxide Synthase Type II
Phosphorylation
Prostaglandin-Endoperoxide Synthases biosynthesis
Prostaglandin-Endoperoxide Synthases genetics
Protein Serine-Threonine Kinases metabolism
Signal Transduction
Anti-Inflammatory Agents therapeutic use
Antineoplastic Agents therapeutic use
NF-kappa B physiology

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