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Killing Mechanisms of Cytotoxic T Lymphocytes.
- Source :
-
News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society [News Physiol Sci] 1998 Feb; Vol. 13, pp. 17-21. - Publication Year :
- 1998
-
Abstract
- Cytotoxic T lymphocytes mediate lysis of target cells by various mechanisms, including exocytosis of lytic proteins (perforin, granzymes) and receptor-ligand binding of Fas/APO molecules. Death of target cells is characterized by either necrosis or apoptosis, depending on the killing mechanism used and on the metabolism of the target cell itself.
Details
- Language :
- English
- ISSN :
- 0886-1714
- Volume :
- 13
- Database :
- MEDLINE
- Journal :
- News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society
- Publication Type :
- Academic Journal
- Accession number :
- 11390753
- Full Text :
- https://doi.org/10.1152/physiologyonline.1998.13.1.17