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Radiographic signs of bone destruction in the arthritic temporomandibular joint with special reference to markers of disease activity. A longitudinal study.
- Source :
-
Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2001 Jun; Vol. 40 (6), pp. 691-4. - Publication Year :
- 2001
-
Abstract
- Objective: To investigate the progression of radiographic changes of the temporomandibular joint (TMJ) with reference to plasma levels of interleukin-1beta (IL-1beta), C-reactive protein (CRP) and disease duration.<br />Methods: Twenty-one patients with chronic inflammatory joint disease and TMJ involvement were included. Individualized tomography of the TMJ was performed twice with an interval of at least 12 months. Blood samples were analysed for IL-1beta and CRP.<br />Results: Significant progression of the overall grade of radiographic changes occurred during the observation period, whereas erosions showed great interindividual variability. Progression of TMJ bone loss was correlated to raised levels of CRP and, in patients with a diagnosis of rheumatoid arthritis, or with shorter duration, also to plasma IL-1beta.<br />Conclusion: Progression of overall grade of radiographic changes in the TMJ occurs in patients with chronic inflammatory joint disease. Raised levels of serum CRP are associated with progression of TMJ bone loss.
- Subjects :
- Adult
Aged
Arthritis blood
Arthritis complications
Bone Diseases etiology
C-Reactive Protein analysis
Disease Progression
Female
Humans
Interleukin-1 blood
Longitudinal Studies
Male
Middle Aged
Radiography
Temporomandibular Joint Disorders blood
Temporomandibular Joint Disorders complications
Arthritis diagnostic imaging
Bone Diseases diagnostic imaging
Temporomandibular Joint Disorders diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1462-0324
- Volume :
- 40
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Rheumatology (Oxford, England)
- Publication Type :
- Academic Journal
- Accession number :
- 11426029
- Full Text :
- https://doi.org/10.1093/rheumatology/40.6.691