Resveratrol, a tumor-suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl-2.

Subjects

Subjects :

Anticarcinogenic Agents pharmacology
Apoptosis Inducing Factor
Biological Transport drug effects
Caspase 2
Caspase 3
Caspase 6
Caspase 9
Caspases metabolism
Cytochrome c Group metabolism
DNA drug effects
DNA metabolism
Enzyme Activation
Flavoproteins metabolism
Humans
Membrane Proteins metabolism
Reactive Oxygen Species metabolism
Receptors, Tumor Necrosis Factor
Receptors, Tumor Necrosis Factor, Member 25
Resveratrol
Rosales chemistry
Signal Transduction drug effects
Signal Transduction physiology
Tumor Cells, Cultured
Apoptosis
Mitochondria metabolism
Proto-Oncogene Proteins c-bcl-2 metabolism
Stilbenes pharmacology

Details

Language :

English

ISSN :

0892-6638

Volume :

15

Issue :

9

Database :

MEDLINE

Journal :

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Publication Type :

Academic Journal

Accession number :

11427503

Full Text :

https://doi.org/10.1096/fj.00-0675fje