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[Experience in the use of vessel due F (sulodexide) in patients with suppurative-necrotic forms of diabetic foot without critical ischemia].
- Source :
-
Terapevticheskii arkhiv [Ter Arkh] 2001; Vol. 73 (4), pp. 31-3. - Publication Year :
- 2001
-
Abstract
- Aim: To evaluate effectiveness of sulodexide in patients with pyonecrotic complications of diabetic foot.<br />Material and Method: Sulodexide was given to 15 patients which were examined for blood fibrinogen, foot tissues saturation with oxygen, microbic contamination of the wound tissue. In addition, ultrasound dopplerography of foot arteries, laser doppler flowmetry were performed.<br />Results: Fibrinogen in peripheral blood fell, arteriovenous shunting diminished, capillary blood flow and oxygen saturation of the tissues improved.<br />Conclusion: Even early sulodexide treatment is effective at different stages of the pathological process in diabetic patients with severe pyonecrotic lesion of the lower limbs as it recovers microcirculatory blood flow.
- Subjects :
- Diabetic Foot pathology
Diabetic Foot physiopathology
Glycosaminoglycans administration & dosage
Humans
Hypoglycemic Agents administration & dosage
Microcirculation
Necrosis
Suppuration
Time Factors
Diabetic Foot drug therapy
Glycosaminoglycans therapeutic use
Hypoglycemic Agents therapeutic use
Subjects
Details
- Language :
- Russian
- ISSN :
- 0040-3660
- Volume :
- 73
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Terapevticheskii arkhiv
- Publication Type :
- Academic Journal
- Accession number :
- 11494443