Synthesis and antimycobacterial activity of [5-(pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives.

Authors :: Mamolo MG
Falagiani V
Zampieri D
Vio L
Banfi E
Source :: Farmaco (Societa chimica italiana : 1989) [Farmaco] 2001 Aug; Vol. 56 (8), pp. 587-92.
Publication Year :: 2001
Abstract: [5-(Pyridin-2-yl)-1,3,4-thiadiazol-2-ylthio]acetic acid arylidene-hydrazide derivatives were synthesized and tested for their in vitro antimycobacterial activity. Some compounds showed a feable activity against a strain of Mycobacterium tuberculosis and a strain of Mycobacterium avium.

Subjects :: Anti-Bacterial Agents chemistry
Anti-Bacterial Agents pharmacology
Microbial Sensitivity Tests
Mycobacterium drug effects
Structure-Activity Relationship
Thiadiazoles chemistry
Thiadiazoles pharmacology
Anti-Bacterial Agents chemical synthesis
Thiadiazoles chemical synthesis

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