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Helicobacter pylori infection in rural China: exposure to domestic animals during childhood and adulthood.
- Source :
-
Scandinavian journal of infectious diseases [Scand J Infect Dis] 2001; Vol. 33 (9), pp. 686-91. - Publication Year :
- 2001
-
Abstract
- Little is known about the mode of transmission of Helicobacter pylori, one of the most common human bacterial infections. Some domestic animals, including the cat, have been suggested as a reservoir of H. pylori disease, but the data have been inconsistent. This paper evaluates the role of exposure to pets and other domestic animals in the etiology of H. pylori in a rural area of China with a high prevalence of H. pylori infection. In this double-blind, population-based, cross-sectional investigation, interviews were completed with 3,288 (1994 seropositive, 1,019 seronegative, 275 indeterminate) H. pylori-infected adults enrolled in a randomized intervention trial in Linqu County, Shandong Province, China. We found no evidence to suggest that exposure to pets or other domestic animals during either childhood or adulthood was related to the prevalence of H. pylori infection. In fact, odds ratios (ORs) were reduced for subjects who had kept a cat (OR = 0.7, 95% CI = 0.4-1.0) or any animal (OR = 0.5, 95% CI = 0.3-0.9) in the house as an adult, or a cat as a child (OR = 0.7, 95% CI =0.5-1.0). ORs were also reduced for all 11 types of animal studied that subjects had kept in their courtyard as an adult. These findings suggest that zoonotic transmission, including that from domestic cats, is an unlikely route of H. pylori infection in this rural Chinese population.
- Subjects :
- Adult
Animals
Animals, Domestic microbiology
Cats microbiology
Child
China epidemiology
Cross-Sectional Studies
Disease Reservoirs statistics & numerical data
Double-Blind Method
Female
Helicobacter Infections blood
Helicobacter Infections etiology
Humans
Male
Middle Aged
Odds Ratio
Rural Health
Seroepidemiologic Studies
Helicobacter Infections epidemiology
Helicobacter Infections transmission
Helicobacter pylori isolation & purification
Zoonoses epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0036-5548
- Volume :
- 33
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Scandinavian journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 11669227
- Full Text :
- https://doi.org/10.1080/00365540110026845