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Sequence variation in the cytochrome oxidase I, internal transcribed spacer 1, and Ts14 diagnostic antigen sequences of Taenia solium isolates from South and Central America, India, and Asia.
- Source :
-
International journal for parasitology [Int J Parasitol] 2001 Dec; Vol. 31 (14), pp. 1601-7. - Publication Year :
- 2001
-
Abstract
- We examined the genetic variability in the pig-human tapeworm, Taenia solium, by sequencing the genes for cytochrome oxidase I, internal transcribed spacer 1, and a diagnostic antigen, Ts14, from individual cysts isolated from Peru, Colombia, Mexico, India, China, and the Philippines. For these genes, the rate of nucleotide variation was minimal. Isolates from these countries can be distinguished based on one to eight nucleotide differences in the 396 nucleotide cytochrome oxidase I (COI) sequence. However, all of the 15 isolates from within Peru had identical COI sequences. The Ts14 sequences from India and China were identical and differed from the Peru sequence by three nucleotides in 333. These data indicate that there is minimal genetic variability within the species T. solium. Minimal variability was also seen in the ITS1 sequence, but this variation was observed within the individual. Twenty-two cloned sequences from six isolates sorted into 13 unique sequences. The variability observed within the sequences from individual cysts was as great as the variability between the isolates.
- Subjects :
- Animals
Base Sequence
China
Colombia
DNA, Helminth isolation & purification
Genetic Variation
Humans
India
Mexico
Molecular Sequence Data
Peru
Philippines
Phylogeny
Sequence Homology, Nucleic Acid
Swine
Taenia classification
Taeniasis parasitology
Antigens, Helminth genetics
DNA, Helminth genetics
DNA, Ribosomal Spacer genetics
Electron Transport Complex IV genetics
Swine Diseases parasitology
Taenia genetics
Taeniasis veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0020-7519
- Volume :
- 31
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- International journal for parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 11730787
- Full Text :
- https://doi.org/10.1016/s0020-7519(01)00295-8