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Identification of foreign gene sequences by transcript filtering against the human genome.

Authors :
Weber G
Shendure J
Tanenbaum DM
Church GM
Meyerson M
Source :
Nature genetics [Nat Genet] 2002 Feb; Vol. 30 (2), pp. 141-2. Date of Electronic Publication: 2002 Jan 14.
Publication Year :
2002

Abstract

We have developed a computational subtraction approach to detect microbial causes for putative infectious diseases by filtering a set of human tissue-derived sequences against the human genome. We demonstrate the potential of this method by identifying sequences from known pathogens in established expressed-sequence tag libraries.

Details

Language :
English
ISSN :
1061-4036
Volume :
30
Issue :
2
Database :
MEDLINE
Journal :
Nature genetics
Publication Type :
Academic Journal
Accession number :
11788827
Full Text :
https://doi.org/10.1038/ng818