Back to Search
Start Over
High rate of recanalization of middle cerebral artery occlusion during 2-MHz transcranial color-coded Doppler continuous monitoring without thrombolytic drug.
- Source :
-
Stroke [Stroke] 2002 Feb; Vol. 33 (2), pp. 626-8. - Publication Year :
- 2002
-
Abstract
- Background and Purpose: Experimental evidence indicates that ultrasound can accelerate thrombolysis. We report our findings on early recanalization during transcranial color-coded Doppler (TCCD) continuous monitoring in acute stroke patients with middle cerebral artery (MCA) main stem occlusion.<br />Methods: We performed continuous TCCD monitorings in 6 consecutive patients with acute MCA main stem occlusion using a 2-MHz transducer. Patients were not treated with recombinant tissue plasminogen activator.<br />Results: Partial recanalization, defined as blunted waveforms, occurred during monitoring in 5 patients (83%). The mean time to beginning of recanalization was 17.2+/-9.6 minutes. Complete recanalization at 24 hours occurred in only 1 patient. The mean National Institutes of Health Stroke Scale score in the patients who recanalized during monitoring was 21.2+/-4.1 at baseline, 19.2+/-5 at 2 hours, and 15.6+/-3.4 at 24 hours (P=0.1).<br />Conclusions: In this short series of patients with acute MCA main stem occlusion, not treated with recombinant tissue plasminogen activator, we found a high rate of early partial recanalization during continuous exposure to 2-MHz ultrasound.
- Subjects :
- Aspirin therapeutic use
Female
Fibrinolysis
Humans
Infarction, Middle Cerebral Artery drug therapy
Male
Middle Aged
Monitoring, Physiologic
Sample Size
Severity of Illness Index
Time Factors
Tomography, X-Ray Computed
Infarction, Middle Cerebral Artery diagnostic imaging
Reperfusion
Ultrasonography, Doppler, Transcranial
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4628
- Volume :
- 33
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Stroke
- Publication Type :
- Academic Journal
- Accession number :
- 11823681
- Full Text :
- https://doi.org/10.1161/hs0202.103073