Determination of iodine values according to Hanus using 1,3-dibromo-5,5-dimethylhydantoin (DBH): analytical methods of pharmacopeias with DBH: part 7.

Authors :: Hilp M
Source :: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2002 Apr 01; Vol. 28 (1), pp. 81-6.
Publication Year :: 2002
Abstract: USP/NF 2000 [The United States Pharmacopeia, Rockville USA, 24th ed., 2000, p. 1868, The National Formulary, 19th ed. 2000] and PH. EUR. 1997 [European Pharmacopoeia, third ed., Council of Europe, Strasbourg, 1997, pp. 63-64] determine the iodine values according to Hanus with iodine monobromide in glacial acetic acid. This reagent can be replaced by a solution of 1,3-dibromo-5,5-dimethylhydantoin (DBH) and potassium iodide or iodine in the same solvent. Both reagents yield equivalent results by means of method comparison according to Passing and Bablok [J. Clin. Chem. Clin. Biochem. 21 (1983) 709; 22, (1984) 431] in relation to the official method of PH. EUR.

Subjects :: Hydantoins chemical synthesis
Hydantoins standards
Iodine chemistry
Iodine standards
Hydantoins analysis
Iodine analysis
Pharmacopoeias as Topic standards

Full Text Access

Tools