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Exacerbation of Avellino corneal dystrophy after laser in situ keratomileusis.
- Source :
-
Cornea [Cornea] 2002 Mar; Vol. 21 (2), pp. 223-6. - Publication Year :
- 2002
-
Abstract
- Purpose: To report a case of Avellino corneal dystrophy that increased in severity 1 year after uncomplicated laser in situ keratomileusis (LASIK) for myopia.<br />Methods: Avellino dystrophy was confirmed by polymerase chain reaction sequencing of DNA from the patient and her parents.<br />Results: Best spectacle-corrected visual acuity decreased from 20/20 to 20/30 12 to 20 months after LASIK owing to opacities that appeared centrally in the corneal stroma and the LASIK flap and remaining posterior stroma interface.<br />Conclusions: LASIK is contraindicated in patients with Avellino corneal dystrophy because vision may be reduced by corneal opacities that appear in the interface of the flap and remaining posterior stroma postoperatively.
- Subjects :
- Adult
Contraindications
Corneal Dystrophies, Hereditary genetics
Corneal Dystrophies, Hereditary physiopathology
Corneal Opacity genetics
Corneal Opacity physiopathology
DNA Mutational Analysis
Disease Progression
Female
Humans
Myopia surgery
Neoplasm Proteins genetics
Polymerase Chain Reaction
Transforming Growth Factor beta genetics
Vision Disorders etiology
Vision Disorders physiopathology
Visual Acuity
Corneal Dystrophies, Hereditary etiology
Corneal Opacity etiology
Extracellular Matrix Proteins
Keratomileusis, Laser In Situ adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0277-3740
- Volume :
- 21
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Cornea
- Publication Type :
- Academic Journal
- Accession number :
- 11862101
- Full Text :
- https://doi.org/10.1097/00003226-200203000-00021