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[Dormant chemotherapy by low-dose FP and low-dose UFT-E in recurrent gastric cancer with long-term survival--a case report].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2002 Feb; Vol. 29 (2), pp. 297-300. - Publication Year :
- 2002
-
Abstract
- We experienced a case of recurrent gastric cancer with a long-term survival. A 64-year-old man was admitted to the hospital for advanced gastric cancer in the upper stomach. Abdominal CT scan revealed para-aortic lymph nodal metastases. The patient underwent total gastrectomy, distal pancreatectomy, splenectomy, left adrenectomy, and left nephrectomy with D4 lymph node dissection, in what was a curability B resection. Conclusive findings were t2 (ss), n4, H0, P0, M0, and stage IVb. One year after the operation, para-aortic lymph node recurrence was evaluated. The patient was treated with low-dose cisplatin-5-FU therapy, and a partial response was observed and continued for over 2 years with an administration of UFT-E (300 mg/day). He died of repeated aggravation of para-aortic lymph node metastases 6 years and 2 months after the operation. We considered that the long-term survival of this patient was attributable to a 3-year tumor dormancy induced by low-dose cisplatin-5-FU therapy and administration of low-dose UFT.
- Subjects :
- Adenocarcinoma, Papillary secondary
Adenocarcinoma, Papillary surgery
Cisplatin administration & dosage
Drug Administration Schedule
Drug Combinations
Fluorouracil administration & dosage
Humans
Lymph Node Excision
Lymphatic Metastasis
Male
Middle Aged
Stomach Neoplasms pathology
Stomach Neoplasms surgery
Survivors
Tegafur administration & dosage
Uracil administration & dosage
Adenocarcinoma, Papillary drug therapy
Antineoplastic Combined Chemotherapy Protocols administration & dosage
Stomach Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 29
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 11865637