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Chemical studies of essential oils of Juniperus oxycedrus ssp. badia.
- Source :
-
Journal of ethnopharmacology [J Ethnopharmacol] 2002 Jun; Vol. 81 (1), pp. 129-34. - Publication Year :
- 2002
-
Abstract
- Leaf and (unripe and ripe) berry essential oils of Juniperus oxycedrus ssp. badia (H. Gay) Debeaux grown wild in Spain have been analysed by capillary GC and GC-MS in combination with retention indices. A seasonal investigation of both leaf and berry oils was also performed. Among the approximately 80 constituents investigated (representing 90-98% of the oils) 60-68 were identified (80-97% of the oil composition). The leaf oils were mainly composed of alpha-pinene (40-57%) and manoyl oxide (5-10%). The (unripe) berry oils were dominated by alpha-pinene (65%) with moderate amounts of myrcene, limonene, germacrene D or gamma-muurolene. Several differences in yields and chemical composition from a qualitative and quantitative point of view were detected when comparing all the oil samples analysed. In addition, two oil samples were examined, but found inactive, against the replication of HIV-1(III(B)) and HIV-2(ROD) in cell culture, whereas the samples were toxic for the cells at a 50% cytotoxic concentration of 106 and 123 microg/ml, respectively.
- Subjects :
- Anti-HIV Agents isolation & purification
Cell Line
Chromatography, Gas
Cytopathogenic Effect, Viral drug effects
Fruit chemistry
HIV physiology
Mass Spectrometry
Plant Leaves chemistry
Anti-HIV Agents chemistry
Anti-HIV Agents pharmacology
HIV drug effects
Juniperus chemistry
Oils, Volatile chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0378-8741
- Volume :
- 81
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of ethnopharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 12020937
- Full Text :
- https://doi.org/10.1016/s0378-8741(02)00045-4