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Neonatal subependymal giant cell astrocytoma.
Neonatal subependymal giant cell astrocytoma.
- Source :
-
Pediatric neurosurgery [Pediatr Neurosurg] 2002 May; Vol. 36 (5), pp. 271-4. - Publication Year :
- 2002
-
Abstract
- Subependymal giant cell astrocytoma (SEGCA) is a benign, slow-growing glial tumor that manifests with signs and symptoms of obstructive hydrocephalus most often in adolescent patients with tuberous sclerosis complex (TSC). Neonatal highly aggressive SEGCA is very rare. We report a 5-month-old child with TSC presenting with a cystic mass lesion in the left frontal lobe as well as multiple other periventricular masses. After initial conservative treatment, the child was readmitted with intractable seizures, a massive increase in the size of the left frontal lobe tumor and obstructive hydrocephalus. Despite surgical interventions, the child succumbed to the intracranial lesions. In this report, we discuss the challenges of managing SEGCA and the importance of further studies, including genetic studies, that may lead to a better understanding of its pathophysiology.<br /> (Copyright 2002 S. Karger AG, Basel)
- Subjects :
- Brain Neoplasms diagnostic imaging
Brain Neoplasms surgery
Female
Glioma, Subependymal diagnostic imaging
Glioma, Subependymal surgery
Humans
Infant, Newborn
Male
Radiography
Brain Neoplasms complications
Brain Neoplasms pathology
Glioma, Subependymal complications
Glioma, Subependymal pathology
Tuberous Sclerosis complications
Subjects
Details
- Language :
- English
- ISSN :
- 1016-2291
- Volume :
- 36
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pediatric neurosurgery
- Publication Type :
- Academic Journal
- Accession number :
- 12053047
- Full Text :
- https://doi.org/10.1159/000058432