[Central nervous system infection complicated after cardiac surgery, a clinical analysis of 10 173 cases].

Objective: To assess the morbidity, mortality, clinical features, death causes, prevention and treatment of patients with central nervous system infection(CNSI) undergoing cardiopulmonary bypass (CPB) surgery.
Methods: 10 173 cases of CNSI undergoing CPB surgery 1984 approximately 1997 were reviewed retrospectively to analysed the morbidity, mortality, clinical features, death causes, prevention and treatment of patients with CNSI after CPB surgery.
Results: After CPB surgery, the general morbidity of neurological complications (NC) was 1.4% (146/10 173), of which cerebrovascular diseases accounted for 59.6% (87/146), and CNSI 7.53%(11/146). The aortic clump time and CPB time were significantly longer in the CNSI group than in the controls (P < 0.01). Death occurred in 44 patients of the NC group, in which CNSI accounted for 18.2%(8/44).
Conclusion: Postoperative CNSI correlates with longer aortic clump time and CPB time during the operation, and high mortality in CNSI group.