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[Autoimmune hepatitis caused by acute hepatitis due to hepatitis A virus].
- Source :
-
Gastroenterologia y hepatologia [Gastroenterol Hepatol] 2002 Oct; Vol. 25 (8), pp. 501-4. - Publication Year :
- 2002
-
Abstract
- We describe the case of a 27-year-old man who presented acute hepatitis due to hepatitis A virus infection. Over the following weeks he consistently presented elevated transaminase levels and jaundice. Antinuclear and anti-smooth muscle antibodies, hypergammaglobulinemia and periportal necrosis were detected in the liver biopsy. The patient was diagnosed with autoimmune hepatitis and responded well to treatment with immunosuppressive drugs. This case, as well as other published reports, suggest that in certain individuals, acute hepatitis A may be the decisive factor leading to autoimmune hepatitis.
- Subjects :
- Acute Disease
Adult
Alanine Transaminase blood
Alkaline Phosphatase blood
Aspartate Aminotransferases blood
Autoantibodies analysis
Autoimmune Diseases blood
Autoimmune Diseases drug therapy
Azathioprine administration & dosage
Azathioprine therapeutic use
Biomarkers
Biopsy
Blood Donors
Drug Therapy, Combination
Hepatitis A blood
Hepatitis, Autoimmune blood
Hepatitis, Autoimmune drug therapy
Humans
Hyperbilirubinemia etiology
Hypergammaglobulinemia etiology
Immunosuppressive Agents therapeutic use
Liver pathology
Male
Prednisone administration & dosage
Prednisone therapeutic use
gamma-Glutamyltransferase blood
Autoimmune Diseases etiology
Hepatitis A complications
Hepatitis, Autoimmune etiology
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0210-5705
- Volume :
- 25
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Gastroenterologia y hepatologia
- Publication Type :
- Academic Journal
- Accession number :
- 12361532