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Dietary oral exposure to l,3,5-trinitro-1,3,5-triazine in the northern bobwhite (Colinus virginianus).
- Source :
-
Environmental toxicology and chemistry [Environ Toxicol Chem] 2003 Feb; Vol. 22 (2), pp. 381-7. - Publication Year :
- 2003
-
Abstract
- The potential risk to wildlife from exposure to explosives, including 1,3,5-trinitro-1,3,5-triazine (RDX), has been an issue at numerous U.S. military installations where these substances are found in soil and water. Presently, no data describing the effects of RDX exposure in avian species exist. Therefore, an acute lethal dose (ALD) and 14- and 90-d subchronic dietary exposures to RDX were evaluated in a species potentially present at many contaminated sites, i.e., the northern bobwhite (Colinus virginianus). The ALDs for females and males were 187 and 280 mg/kg, respectively. Data from the 14-d dietary trial suggested that RDX exposure inhibited food consumption, weight gain, and egg production. Dietary RDX exposure for 90-d produced a dose-dependant decreasing trend in total feed consumption, total egg production, and hen-housed production parameters. These collective data suggest that quail may respond differently to oral RDX exposure compared with mammals.
- Subjects :
- Administration, Oral
Animal Feed
Animals
Apoptosis drug effects
Blood Cell Count
Blood Proteins analysis
Body Weight drug effects
Colinus blood
Female
Leukocytes drug effects
Liver drug effects
Liver pathology
Male
Organ Size drug effects
Spleen drug effects
Spleen pathology
Toxicity Tests, Acute
Toxicity Tests, Chronic
Colinus growth & development
Environmental Pollutants toxicity
Toxicity Tests
Triazines toxicity
Subjects
Details
- Language :
- English
- ISSN :
- 0730-7268
- Volume :
- 22
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Environmental toxicology and chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 12558171