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Bacterial RNA polymerases: the wholo story.
- Source :
-
Current opinion in structural biology [Curr Opin Struct Biol] 2003 Feb; Vol. 13 (1), pp. 31-9. - Publication Year :
- 2003
-
Abstract
- Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.
- Subjects :
- Bacteria chemistry
Bacteria enzymology
Bacteria metabolism
Bacterial Proteins chemistry
Bacterial Proteins metabolism
Binding Sites
Crystallography methods
DNA metabolism
DNA-Directed RNA Polymerases metabolism
Holoenzymes chemistry
Holoenzymes metabolism
Macromolecular Substances
Promoter Regions, Genetic
Protein Binding
Protein Conformation
Protein Structure, Tertiary
RNA biosynthesis
Sigma Factor metabolism
Thermus enzymology
Thermus metabolism
DNA chemistry
DNA-Directed RNA Polymerases chemistry
Models, Molecular
RNA chemistry
Sigma Factor chemistry
Thermus chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 0959-440X
- Volume :
- 13
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Current opinion in structural biology
- Publication Type :
- Academic Journal
- Accession number :
- 12581657
- Full Text :
- https://doi.org/10.1016/s0959-440x(02)00005-2