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[Phthalimide derivatives of pyrimidine and thiazole heterocyclics].
- Source :
-
Il Farmaco; edizione scientifica [Farmaco Sci] 1976 Feb; Vol. 31 (2), pp. 133-9. - Publication Year :
- 1976
-
Abstract
- The synthesis of some phthalimido-derivatives of the pyrimidine and thiazole ring systems is described. The functional groups have been suitably selected to enhance structural analogy with the pairs of pyrimidine and purine bases present in nucleic acids. In preliminary tests some of these compounds have shown inhibitory activity towards RNA polymerase reaction in vitro.
Details
- Language :
- Italian
- ISSN :
- 0430-0920
- Volume :
- 31
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Il Farmaco; edizione scientifica
- Publication Type :
- Academic Journal
- Accession number :
- 1261665