E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

Subjects

Subjects :

Adenosine Triphosphate physiology
Genetic Variation
Humans
Potassium Channels, Inwardly Rectifying metabolism
Receptors, Cytoplasmic and Nuclear genetics
Transcription Factors genetics
Diabetes Mellitus, Type 2 genetics
Genetic Predisposition to Disease
Islets of Langerhans metabolism
Polymorphism, Single Nucleotide
Potassium Channels, Inwardly Rectifying genetics
White People genetics

Details

Language :

English

ISSN :

0012-186X

Volume :

46

Issue :

1

Database :

MEDLINE

Journal :

Diabetologia

Publication Type :

Editorial & Opinion

Accession number :

12643262

Full Text :

https://doi.org/10.1007/s00125-002-0947-x