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Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system.
- Source :
-
Journal of immunological methods [J Immunol Methods] 2003 Apr 01; Vol. 275 (1-2), pp. 133-6. - Publication Year :
- 2003
-
Abstract
- The use of the Immulite Automated Immunoassay system is becoming an increasingly popular method for accurate and fast measurement of sIL-2R in serum. Here, we report that detection of sIL-2R using the Immulite Immunoassay system in serum samples of patients who are treated with basiliximab, a monoclonal antibody against the alpha-chain of the IL-2 receptor, may lead to false measurements.
- Subjects :
- Antibodies, Monoclonal therapeutic use
Basiliximab
Binding, Competitive
Humans
Immunosuppressive Agents blood
Immunosuppressive Agents therapeutic use
Liver Transplantation immunology
Solubility
T-Lymphocytes immunology
Time Factors
Antibodies, Monoclonal blood
Immunoassay methods
Receptors, Interleukin-2 blood
Recombinant Fusion Proteins
Subjects
Details
- Language :
- English
- ISSN :
- 0022-1759
- Volume :
- 275
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- Journal of immunological methods
- Publication Type :
- Academic Journal
- Accession number :
- 12667677
- Full Text :
- https://doi.org/10.1016/s0022-1759(03)00016-4